
ASV default settings
Only three therapy parameters to set
EPAP 5 cm H
2
O
Min PS 3 cm H
2
O
Max PS 15 cm H
2
O
Ramp OFF
ASVAuto default settings
Only four therapy parameters to set
Min EPAP 4 cm H
2
O
Max EPAP 15 cm H
2
O
Min PS 3 cm H
2
O
Max PS 15 cm H
2
O
Ramp OFF
VPAP Adapt Therapy Titration Protocol
Indications for ASV therapy
•Periodic breathing, both normocapnic
and hypocapnic
•Other forms of central and concomitant
obstructive events
1
(mixed sleep apnea)
•Complex sleep apnea (CompSA)
2
The guidelines below can help to set up
and treat patients with central breathing
disorders using the standard ASV mode
in ResMed’s adaptive servo-ventilation
(ASV) devices. This guidance is intended
for in-lab titration and should not super-
cede direction by a physician.
For more details on therapy settings
and adjustments, please refer to
the Clinical Guide for the specific
therapy device.
Begin therapy with default settings
Increase EPAP by 1 cm H
2
O every
20 minutes until obstructive
events are eliminated
Obstructive events eliminated?
Any obstructive apneas,
hypopneas or RERAs?
Excessive leak
Adjust or change
mask until leak fixed
Leak is greater
than 24 L/min
1 Allam JS et al. Efficacy of adaptive servo-ventilation in treatment of complex and central sleep apnea syndromes. Chest 2007; 132(6): p. 1839-46
2 Morgenthaler T I et al. Adaptive servo-ventilation versus noninvasive positive pressure ventilation for central, mixed, and complex sleep apnea syndromes. Sleep 2007; 30(4): p. 468-75
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VPAP Adapt Titration
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